Fumihiko Hirai Selected Research

Creatinine

4/2019

Phase I dose-escalation study of capmatinib (INC280) in Japanese patients with advanced solid tumors.

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Fumihiko Hirai Research Topics

Disease

30	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2022 - 04/2010
27	Neoplasms (Cancer) 05/2022 - 06/2011
10	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2010
8	Adenocarcinoma 01/2018 - 05/2010
6	Adenocarcinoma of Lung 06/2019 - 09/2013
4	Neoplasm Metastasis (Metastasis) 06/2018 - 01/2016
4	Thymoma (Thymic Carcinoma) 04/2016 - 10/2013
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2018 - 04/2015
3	Malignant Mesothelioma 06/2018 - 08/2014
3	Pneumonia (Pneumonitis) 01/2018 - 01/2016
2	Nausea 04/2019 - 01/2016
2	Lymphatic Metastasis 04/2018 - 01/2018
2	Pleural Effusion (Pleural Effusions) 12/2017 - 03/2014
2	Disease Progression 01/2016 - 10/2014
2	Fatigue 02/2015 - 09/2013
2	Neutropenia 02/2015 - 09/2013
2	Lymphoma (Lymphomas) 07/2014 - 01/2010
1	Vasculitis (Vasculitides) 01/2021
1	Dysbiosis 01/2021
1	Diarrhea 04/2019
1	Vomiting 04/2019
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 11/2018
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2018
1	Brain Neoplasms (Brain Tumor) 01/2018
1	Pulmonary Edema 01/2018
1	Febrile Neutropenia 01/2018
1	Breast Neoplasms (Breast Cancer) 10/2017
1	Hypotension (Low Blood Pressure) 09/2017
1	Anorexia 09/2017
1	Fever (Fevers) 01/2016
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Melanoma (Melanoma, Malignant) 01/2016
1	Chemical and Drug Induced Liver Injury 07/2015

Drug/Important Bio-Agent (IBA)

9	LigandsIBA 06/2019 - 12/2017
9	ErbB Receptors (EGF Receptor)IBA 05/2019 - 04/2010
5	Pharmaceutical PreparationsIBA 04/2019 - 11/2011
5	Cisplatin (Platino)FDA LinkGeneric 09/2017 - 11/2011
4	PlatinumIBA 10/2021 - 10/2013
4	Anaplastic Lymphoma KinaseIBA 09/2018 - 09/2013
4	Alanine Transaminase (SGPT)IBA 09/2017 - 09/2013
3	pembrolizumabIBA 01/2021 - 01/2016
3	B7-H1 AntigenIBA 06/2019 - 01/2018
3	ceritinibIBA 09/2018 - 07/2015
3	Pemetrexed (MTA)FDA Link 09/2017 - 08/2014
3	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2016 - 09/2013
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 07/2014 - 01/2010
2	Immune Checkpoint InhibitorsIBA 01/2022 - 11/2018
2	Biomarkers (Surrogate Marker)IBA 06/2019 - 10/2018
2	xylometazoline (stas)IBA 01/2018 - 01/2018
2	Docetaxel (Taxotere)FDA Link 01/2018 - 02/2015
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 07/2017 - 05/2014
2	AnthracyclinesIBA 01/2016 - 10/2013
2	Tyrosine Kinase InhibitorsIBA 03/2015 - 04/2010
2	Gemcitabine FDA Link 10/2014 - 08/2014
2	Vinorelbine (Navelbine)FDA LinkGeneric 08/2014 - 02/2014
2	Phosphotransferases (Kinase)IBA 07/2014 - 01/2010
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2022
1	Proton Pump InhibitorsIBA 01/2022
1	CreatinineIBA 04/2019
1	capmatinibIBA 04/2019
1	TabletsIBA 04/2019
1	Creatine Kinase (Creatine Phosphokinase)IBA 03/2019
1	alectinibIBA 09/2018
1	Enhancer of Zeste Homolog 2 ProteinIBA 06/2018
1	Histone MethyltransferasesIBA 06/2018
1	C-Reactive ProteinIBA 06/2018
1	AlbuminsIBA 06/2018
1	AfatinibIBA 04/2018
1	ChemokinesIBA 01/2018
1	ImmunosorbentsIBA 01/2018
1	InterferonsIBA 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2018
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	TroponinIBA 01/2018
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2018
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2018
1	Chemokine CXCL12IBA 01/2018
1	AZD 6244IBA 01/2018
1	EnzymesIBA 01/2018
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2017
1	Protein Isoforms (Isoforms)IBA 09/2017
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 09/2017
1	Aspartic Acid (Aspartate)FDA Link 09/2017
1	capivasertibIBA 04/2016
1	Imatinib Mesylate (Gleevec)FDA Link 04/2016
1	Sunitinib (Sutent)FDA Link 04/2016
1	Monoclonal AntibodiesIBA 01/2016
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2016
1	Carcinoembryonic AntigenIBA 01/2016

Therapy/Procedure

17	Drug Therapy (Chemotherapy) 10/2021 - 04/2010
15	Therapeutics 05/2022 - 12/2011
7	Chemoradiotherapy 03/2019 - 05/2010
4	Radiotherapy 10/2017 - 11/2011
3	Immunotherapy 05/2022 - 06/2019
3	Pneumonectomy (Lung Volume Reduction) 03/2019 - 02/2014
2	Intravenous Infusions 01/2016 - 06/2011
1	Lymph Node Excision (Lymph Node Dissection) 12/2017
1	Molecular Targeted Therapy 04/2016
1	Metastasectomy 01/2016